Ontario's Special Investigations Unit is investigating after Toronto Police opened fire on a car that was seen leaving the scene of a shooting on the Exhibition grounds.

The situation got out of control when a fight broke out near Muzik nightclub at around 3:00am Sunday.

Soon after, police officers heard gunshots.  2 males were hit, one left with serious injuries.

A black, 4-door Honda Accord was seen driving away.

When the car refused to stop, police opened fire.

Two of the three people inside were hit by "projectiles," the SIU says.

They remain at St. Mike's Hospital.

Another person in the car was not injured and has been taken into custody by Toronto Police.

In a statement, the president of Muzik nightclub says the shooting did not take place on their property.

The SIU investigates incidents involving police where someone has died, been seriously injured, or there are allegations of sexual assault.

(with files from James Moore)