If you're driving out the Kingston way Wednesday morning, this will be crucial for you to know.
Provincial police have closed all lanes of the eastbound 401 between Cobourg to Grafton.
Reportedly there are several tractor-trailers involved in a chain-reaction collision through that stretch and it'll take a while for the clean-up process to be completed.
Northumberland OPP hasn't indicated whether there were any injuries, or what may have caused the collision.
OPP predicted the closure would last between 5 and 6 hours.