Police have identified the woman stabbed to death Friday night.
Sarah Vermelhudo, 38, of Toronto, was pronounced dead in hospital.
The stabbing happened in the College Street and Dufferin Street area around 8 p.m.
Another woman was also stabbed.
She is listed in stable condition.
Shayne MacDonald, 21, of Toronto, is wanted for second-degree murder and attempted murder.
He is described as 5'10", 160 lbs., with light-brown hair.
According to police, he is considered violent, armed and dangerous.
If located, do not approach. Call 9-1-1 immediately.
With files from Corinne Van Dusen