It took several hours to clean up and reopen the 401 in the Bowmanville area after numerous crashes caused the closure of the highway Saturday.
The westbound lanes were closed at Liberty Street, eastbound at Holt Road.
One of the collisions involved aobut 20 vehicles.
A video taken by someone standing on a overpass at the time the collisions happened.
(YouTube video from aaron c)
Environment Canada says a snow band off Lake Ontario brought low visibility and some accumulating snow to the area.
Police say several people were taken to hospital with minor injuries.
The highway re-opened before 11 p.m.